Response to Leptin-deficient mice are not hypothermic, they are anapyrexic
نویسندگان
چکیده
منابع مشابه
Leptin-deficient mice are not hypothermic, they are anapyrexic
Having just published a paper with the explicit title “Leptin Raises Defended Body Temperature without Activating Thermogenesis” [1] we are surprised by a recent paper in Molecular Metabolism [2], stating that we have shown that leptin functions by an “increase of the body temperature threshold for activating thermogenesis.” In contrast to what is implied, we are fully in agreement concerning e...
متن کاملResponse to Leptin-deficient mice are not hypothermic, they are anapyrexic
To the Editor: The Comment by Fisher, Cannon and Nedergaard [1] on our recent paper [2] advocates use of the term ‘anapyrexia,’ which connotes a biologically defended decrease of body temperature; e.g., the opposite of a fever, to describe the subnormal core temperature of leptin-deficient ob/ob mice. Another option is the conjunction ‘regulated hypothermia’ [3], based on the Glossary of Terms ...
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Bayes factors have been ooered by Bayesians as alternatives to P-values (or significance probabilities) for testing hypotheses and for quantifying the degree to which observed data support or connict with a hypothesis. Schervish (1996) showed how the interpretation of P-values as measures of support suuers a certain logical aw. In this paper, we show how Bayes factors suuer that same aw. We inv...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2017
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2017.01.008